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Antigenic Specificity | PKM2 |
Clone | [1F2-F4-H11] |
Host Species | Mouse |
Reactive Species | human, mouse, monkey |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 0.7mg/mL |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. |
Immunogen | Immunogen: Purified recombinant human PKM2 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of PKM2 and does not cross-react with related proteins. Sequence Similarities: Belongs to the pyruvate kinase family. |
Other Names | [CTHBP; Cytosolic thyroid hormone binding protein; Cytosolic thyroid hormone-binding protein; KPYM_HUMAN; MGC3932; OIP 3; OIP-3; OIP3; OPA interacting protein 3; Opa-interacting protein 3; p58; PK muscle type; PK, muscle type; PK2; PK3; PKM; PKM2; pykm; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; pyruvate kinase PKM; Pyruvate kinase, muscle 2; TCB; THBP1; Thyroid hormone binding protein 1; Thyroid hormone binding protein cytosolic; Thyroid hormone-binding protein 1; Tumor M2 PK; Tumor M2-PK], [PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30] |
Gene, Accession # | [PKM2], Gene ID: 5315, NCBI: NP_001193725.1, UniProt: P14618 |
Catalog # | MBS475183 |
Price | $335 |
Order / More Info | PKM2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |