CTCF Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCTCF
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, monkey
IsotypeIgG1
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: CTCF antibody detects endogenous levels of total CTCF. Description: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promo
ImmunogenImmunogen: Purified recombinant fragment of human CTCF expressed in E. Coli Subcellular Location: Nucleus > Nucleoplasm. Chromosome. Chromosome > Centromere. May translocate to the nucleolus upon cell differentiation. Associates with both centromeres and chromosomal arms during metaphase. Associates with the H19 ICR in mitotic chromosomes. May be preferentially excluded from heterochromatin during interphase. Tissue Specificity: Ubiquitous. Absent in primary spermatocytes.
Other Names[11 zinc finger protein; 11 zinc finger transcriptional repressor; 11-zinc finger protein; CCCTC binding factor (zinc finger protein); CCCTC binding factor; CCCTC-binding factor; Ctcf; CTCF_HUMAN; CTCFL paralog; MRD21; Transcriptional repressor CTCF]
Gene, Accession #[CTCF], Gene ID: 10664, NCBI: NP_001177951.1, UniProt: P49711
Catalog #MBS9602686
Price$235, $295, $370
Order / More InfoCTCF Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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