Histone H2AX Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHistone H2AX
Clone[RM214]
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
FormatProtein A purified
Size0.025 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB); Immunocytochemistry (ICC); ELISA (EIA); Multiplex
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DescriptionRabbit monoclonal antibody to detect Histone H2AX. Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin; limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation; DNA repair; DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones; also called histone code; and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-termi
ImmunogenImmunogen: A peptide corresponding to the C-terminus of human Histone H2AX
Other Names[H3F3A; H3.3A; H3F3; H3F3B; H3.3B], [H2AFX]
Gene, Accession #[H2AX], Gene ID: 3014, NCBI: NP_002096.1, UniProt: P16104
Catalog #MBS846021
Price$245
Order / More InfoHistone H2AX Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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