Prion Protein, Chicken Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPrion Protein, Chicken
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.2 mL
Concentrationn/a
ApplicationsImmunocytochemistry (ICC)
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DescriptionPrion protein is the protein responsible for human Creutzfeldt-Jakob Disease (CJD), and somatic mutations of the prion gene are responsible for Gerstmann-Straussler-Scheinker disease and Fatal Familial Insomnia. The bovine homolog of the prion protein is responsible for bovine Spongioform Encephalopathy (BSE), also known as Mad Cow Disease. In all cases, the prion protein has two folding states, with one state being the normal non-pathological form, and the other state inducing a spongioform encephalopathy. Normal prion proteins produced naturally in the brain interact with the amyloid-b peptides that are hallmarks of Alzheimer's disease. Blocking this interaction in preparations made from mouse brains halted some neurological defects c
ImmunogenImmunogen: Recombinant fragment of the Human Prion
Other Names[Prion protein; Major prion protein; alternative prion protein; major prion protein; prion protein; ASCR; PrP27-30; PrP33-35C; CD_antigen: CD230], [PRNP; PRNP; CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C; ALTPRP; PRIP; PRP; PrP]
Gene, Accession #[CD230], Gene ID: 5621, NCBI: AAH22532.1
Catalog #MBS555366
Price$430
Order / More InfoPrion Protein, Chicken Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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