Edit |   |
---|---|
Antigenic Specificity | SFN (Center), 120-149 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SFN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the Central region of human SFN. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity).p53-regulated inhibitor of G2/M progression. |
Immunogen | n/a |
Other Names | [14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin; SFN; HME1] |
Gene, Accession # | [SFN], Gene ID: 2810, NCBI: NP_006133.1, UniProt: P31947 |
Catalog # | MBS9204224 |
Price | $165, $370 |
Order / More Info | SFN (Center), 120-149 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ren, H.Z., et al. Dig. Dis. Sci. 55(9):2552-2560(2010) Liu, Y., et al. Brain Res. 1336, 98-102 (2010) : Pei, H.P., et al. Zhonghua Wei Chang Wai Ke Za Zhi 13(3):213-215(2010) Syrjanen, S., et al. Am. J. Clin. Pathol. 133(2):232-240(2010) Zurita, M., et al. BMC Cancer 10, 217 (2010) : |