IL-17A Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-IL-17A antibody, protein, ELISA kits.
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| Antigenic Specificity | IL-17A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL-17A is a cystine-linked homodimeric pro-inflammatory cytokine produced by Th17 cells, a distinct CD4+ T cell lineage (1, 2). IL-17A stimulates the production of the pro-inflammatory cytokines IL-1beta, TNF-alpha, and IL-6. IL-17A also induces production of the neutrophil chemoattractants IL-8, CXCL1, and CXCL6 thereby bridging adaptive and innate immunity (1, 2). IL-17A is intimately involved in mucosal immunity against bacterial infections (1, 3) and has a putative role in some autoimmune disorders (1, 4). IL-17A effects appear to be exerted primarily through binding to the IL-17RA (5). IL-17A binding induces production of cytokines, chemokines and other proteins through activation of the Erk1/2 MAP kinase, PI3K/Akt, p38, and NF-kappaB |
| Immunogen | Immunogen: Recombinant protein of human IL17A Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [IL17A; CTLA8; IL-17; IL-17A; IL17] |
| Gene, Accession # | [IL-17A], Gene ID: 3605, NCBI: NP_002181.1, UniProt: Q16552 |
| Catalog # | MBS8503471 |
| Price | $310 |
| Order / More Info | IL-17A Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kolls, J.K. and Linden, A. (2004) Immunity 21, 467-76. 2. Liang, S.C. et al. (2006) J Exp Med 203, 2271-9. 3. Dubin, P.J. and Kolls, J.K. (2008) Immunol Rev 226, 160-71. 4. Zrioual, S. et al. (2009) J Immunol 182, 3112-20. 5. Wright, J.F. et al. (2008) J Immunol 181, 2799-805. 6. Rahman, M.S. et al. (2006) J Immunol 177, 4064-71. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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