BRD3 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | BRD3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Nuclear protein in testis (NUT) is normally confined to the germ cells of the testis and ovary (1, 2). NUT midline carcinoma (NMC) is a recently recognized cancer that is defined by the presence of chromosomal rearrangements involving the NUT gene on chromosome 15q14 (3). In most cases the chromosomal translocation occurs between NUT and BRD4 on chromosome 19, resulting in the formation of a BRD4-NUT fusion protein. In the remaining tumors, variant NUT rearrangements are present involving BRD3, a very close homolog of BRD4. BRD4-NUT and BRD3-NUT encode fusion proteins that appear to contribute to carcinogenesis by blocking epithelial cell differentiation. NMCs, which are aggressive and highly lethal carcinomas, are morphologically indisting |
| Immunogen | Immunogen: Recombinant protein of human BRD3 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [FLJ23227; FLJ41328; KIAA0043; ORFX; RING3L] |
| Gene, Accession # | [BRD3], Gene ID: 8019, NCBI: NP_031397.1, UniProt: Q15059 |
| Catalog # | MBS8505668 |
| Price | $310 |
| Order / More Info | BRD3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. French, C.A. et al. (2003) Cancer Res 63, 304-7. 2. Haack, H. et al. (2009) Am J SurgPathol 33, 984-91. 3. French, C.A. et al. (2008) Oncogene 27, 2237-42. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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