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Antigenic Specificity | Cytochrome P450 2E1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Cytochrome P450 2E1(CYP2E1) detection. Tested with WB, IHC-P in Mouse, Rat. Background: CYP2E1, also known as P450IIE1, is a member of the P450IIE subfamily which is ethanol-inducible. It has at least 1 gene which is mapped to 10q24.3-qter, and a second is likely in rat and in man. Both the rat and human proteins encoded by this gene contain 493 amino acids and calculated molecular masses of 56,634 and 56,916 daltons, respectively. In addition, genetic polymorphisms in the 5-prime flanking region of the human P450IIE1 gene affected its binding of transacting factor and changed its transcriptional regulation, which may lead to interindividual differences of microsomal drug oxidation activity. P |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse Cytochrome P450 2E1 (94-112aa KNEFSGRGDIPVFQEYKNK), identical to the related rat sequence. |
Other Names | [Cytochrome P450 2E1; cytochrome P450, family 2, subfamily E, polypeptide 1; 4-nitrophenol 2-hydroxylase; CP2E1_HUMAN; CPE 1; CPE1; CYP2E; CYP2E1; CYPIIE1; Cytochrome P450 2E1; Cytochrome P450 family 2 subfamily E polypeptide 1; Cytochrome P450 isozyme 3A; Cytochrome P450 LM3A; Cytochrome P450 subfamily IIE(ethanol inducible) polypeptide 1; Cytochrome P450 subfamily IIE polypeptide 1; Cytochrome P450, family 2, subfamily e, polypeptide 1; cytochrome P450, subfamily IIE(ethanol-inducible), polypeptide 1; Cytochrome P450, subfamily IIE; Cytochrome P450-ALC; Cytochrome P450-J; Cytochrome P450RLM6; EC 1.14.13.-; EC 1.14.13.n7; Ethanol-inducible P450; Flavoprotein linked monooxygenase; Flavoprotein-linked monooxygenase; MGC133529; Microsomal monooxygenase; OTTHUMP00000020813; OTTHUMP00000046571; P450 ALC; p450; P450 J; P450-J; P450C2E; P450J; P450RLM6; Xenobiotic monooxygenase], [Cyp2e1; Cyp2e1; Cyp2e; Cyp2e; Cyp2e-1] |
Gene, Accession # | [CYP2E1], Gene ID: 13106, NCBI: Q05421.1, UniProt: Q05421 |
Catalog # | MBS176396 |
Price | $315 |
Order / More Info | Cytochrome P450 2E1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |