Glypican-3 (GPC3) (Hepatocellular Carcinoma Marker) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Glypican-3 (GPC3) (Hepatocellular Carcinoma Marker) antibody, protein, ELISA kits.
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| Antigenic Specificity | Glypican-3 (GPC3) (Hepatocellular Carcinoma Marker) |
| Clone | [1G12 + GPC3/863] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Glypican-3 (GPC3) is an integral membrane protein that is mutated in the Simpson-Golabi-Behmel syndrome (SGBS). SGBS is characterized by pre- and post-natal overgrowth and is a recessive X-linked condition. GPC3 may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor. In patients with HCC, GPC3 is overexpressed in neoplastic liver tissue and elevated in serum, but is undetectable in normal liver, benign liver, and the serum of healthy donors. GPC3 expression is also found to be higher in HCC liver tissue than in cirrhotic liver or liver with focal lesions such as dyspla |
| Immunogen | Immunogen: Recombinant fragment containing amino acids 511-580 of human glypican-3 (1G12); Recombinant full-length human GPC3 protein (GPC3/863) |
| Other Names | [DGSX; Glypican proteoglycan 3; GPC3; GTR2-2; Heparan sulphate proteoglycan; Intestinal protein OCI-5; MXR7; OCI-5; SDYS; Secreted glypican-3; SGBS1], [GPC3; GPC3; SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; OCI5] |
| Gene, Accession # | [GPC3], Gene ID: 2719, NCBI: NP_001158089.1, UniProt: P51654 |
| Catalog # | MBS438659 |
| Price | $190, $340, $340 |
| Order / More Info | Glypican-3 (GPC3) (Hepatocellular Carcinoma Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yan, B., et al. 2011. Expression and clinicopathologic significance of glypican 3 in hepatocellular carcinoma. Ann. Diagn. Pathol. 15: 162-169. Ning, S., et al. 2012. Glypican-3, a novel prognostic marker of hepatocellular cancer is related with postoperative metastasis and recurrence in hepatocellular cancer patients. Mol. Biol. Rep. 39: 351-357. Zhang, L., et al. 2012. Glypican-3 as a potential differential diagnosis marker for hepatocellular carcinoma: a tissue microarray-based study. Acta Histochem. 114: 547-552 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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