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Antigenic Specificity | Human RISC-loading complex subunit TARBP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. This is achieved |
Immunogen | Immunogen: Recombinant human RISC-loading complex subunit TARBP2 protein (1-366aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27612 / sc-292550 / sc-134110 |
Other Names | [TAR RNA-binding protein 2; Trans-activation-responsive RNA-binding protein; TARBP2; TRBP], [TARBP2; TARBP2; LOQS; TRBP; TRBP1; TRBP2] |
Gene, Accession # | [TARBP2], Gene ID: 6895, NCBI: NP_004169.3, UniProt: Q15633 |
Catalog # | MBS1498715 |
Price | $120, $160 |
Order / More Info | Human RISC-loading complex subunit TARBP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |