Topoisomerase II beta Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTopoisomerase II beta
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total topoisomerase II b protein. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.Ren?| M. Linka, Nucleic Acids Res., May 2007; 10.1093.John R. Jenkins, Nucleic Acids Res., Nov 1992; 20: 5587 - 5592. Kathryn L. Gilroy, Nucleic Acids Res., Mar 2006; 34: 1597 - 1607.Sophie Dereuddre, Cancer Res., Oct 1997; 57: 4301 - 4308.
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human topoisomerase II b.
Other Names[Topoisomerase II b; DNA topoisomerase II; beta isozyme; EC 5.99.1.3; TP2B; TOP2B]
Gene, Accession #Gene ID: 7155, NCBI: NP_001059.2, UniProt: Q02880
Catalog #MBS9406284
Price$200, $255
Order / More InfoTopoisomerase II beta Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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