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Antigenic Specificity | Topoisomerase II beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total topoisomerase II b protein. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.Ren?| M. Linka, Nucleic Acids Res., May 2007; 10.1093.John R. Jenkins, Nucleic Acids Res., Nov 1992; 20: 5587 - 5592. Kathryn L. Gilroy, Nucleic Acids Res., Mar 2006; 34: 1597 - 1607.Sophie Dereuddre, Cancer Res., Oct 1997; 57: 4301 - 4308. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human topoisomerase II b. |
Other Names | [Topoisomerase II b; DNA topoisomerase II; beta isozyme; EC 5.99.1.3; TP2B; TOP2B] |
Gene, Accession # | Gene ID: 7155, NCBI: NP_001059.2, UniProt: Q02880 |
Catalog # | MBS9406284 |
Price | $200, $255 |
Order / More Info | Topoisomerase II beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |