MARCH8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MARCH8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MARCH8 antibody detects endogenous levels of total 42437. Function: E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.Subunit Structure: Interacts with CD86.Similarity: The RING-CH-type zinc finger domain is required for E3 ligase activity. |
| Immunogen | Immunogen: A synthesized peptide derived from human MARCH8 Subcellular Location: Cytoplasmic Vesicle Membrane. Lysosome Membrane. Early Endosome Membrane. Tissue Specificity: Broadly expressed. Present in immature dendritic cells (at protein level). |
| Other Names | [c MIR; c-MIR; Cellular modulator of immune recognition; E3 ubiquitin protein ligase MARCH8; E3 ubiquitin-protein ligase MARCH8; MARCH 8; MARCH VIII; MARCH-VIII; MARCH8; MARH8_HUMAN; Membrane associated RING CH protein VIII; Membrane associated ring finger (C3HC4) 8; Membrane associated RING finger protein 8; Membrane-associated RING finger protein 8; Membrane-associated RING-CH protein VIII; MIR; OTTHUMP00000058921; RING finger protein 178; RNF178] |
| Gene, Accession # | [MARCH8], Gene ID: 220972, NCBI: NP_001002266.1, UniProt: Q5T0T0 |
| Catalog # | MBS9609801 |
| Price | $240, $280 |
| Order / More Info | MARCH8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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