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Antigenic Specificity | Phospho-TBC1D4-T642 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the Tre-2/BUB2/CDC16 domain family. The protein encoded by this gene is a Rab-GTPase-activating protein, and contains two phopshotyrosine-binding domains (PTB1 and PTB2), a calmodulin-binding domain (CBD), a Rab-GTPase domain, and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin-dependent trafficking of the glucose transporter 4 (GLUT4), important for removing glucose from the bloodstream into skeletal muscle and fat tissues. Reduced expression of this gene results in an increase in GLUT4 levels at the plasma membrane, suggesting that this protein is important in intracellular retention of GLUT4 under basal conditions. When exposed to insu |
Immunogen | Immunogen: A synthetic phosphorylated peptide around T642 of human TBC1D4 (NP 055647.2). |
Other Names | [TBC1 domain family member 4 isoform 1; TBC1 domain family member 4; TBC1 domain family member 4; TBC1 domain family member 4; Akt substrate of 160 kDa] |
Gene, Accession # | [TBC1D4], Gene ID: 9882, NCBI: NP_055647.2, UniProt: O60343 |
Catalog # | MBS8574619 |
Price | $280 |
Order / More Info | Phospho-TBC1D4-T642 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |