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Antigenic Specificity | Phospho-MAP3K1 (Thr1402) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-MAP3K1 (Thr1402) antibody detects endogenous levels of MAP3K1 only when phosphorylated at Thr1402. Function: Component of a protein kinase signal transduction cascade (PubMed:9808624). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:9808624). May phosphorylate the MAPK8/JNK1 kinase (PubMed:17761173). Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:9808624).Subunit Structure: Binds both upstream activators and downstream substrates in multimolecular complexes through its N-terminus (PubMed:9808624). Oligomerizes after binding MAP2K4 or TRAF2 (PubMed:9808624). Interacts with AXIN1 (PubMed:12223491, PubMed:15262978). Interacts (via the ki |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-MAP3K1 (Thr1402) |
Other Names | [M3K1_HUMAN; MAP3K1; MAPK/ERK kinase kinase 1; MAPKKK1; MEK kinase 1; MEKK 1; Mekk; MEKK1; Mitogen activated protein kinase kinase kinase 1; Mitogen activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; Mitogen-activated protein kinase kinase kinase 1; SRXY6] |
Gene, Accession # | [MAP3K1], Gene ID: 4214, NCBI: NP_005912.1, UniProt: Q13233 |
Catalog # | MBS9609058 |
Price | $240, $280 |
Order / More Info | Phospho-MAP3K1 (Thr1402) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |