PDCD1/PD1/CD279 (Programmed Cell Death 1) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPDCD1/PD1/CD279 (Programmed Cell Death 1)
Clone[PDCD1/1410R]
Host SpeciesRabbit
Reactive Specieshuman.
IsotypeIgG
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
ImmunogenImmunogen: Human full-length recombinant PDCD1 protein Cellular Localization: Cell Surface & Cytoplasmic
Other Names[CD279; hPD-1; hSLE1; PD1; PDCD1; Programmed Cell Death Protein 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2]
Gene, Accession #[PDCD1], Gene ID: 5133, NCBI: NP_005009.2, UniProt: Q15116
Catalog #MBS4380145
Price$190, $340, $340
Order / More InfoPDCD1/PD1/CD279 (Programmed Cell Death 1) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesRoncador, G., Verdes-Montenegro, J.F.G., Tedoldi, S., Paterson, J.C., Klapper, W., Ballabio, E., Maestre, L., Pileri, S., Hansmann, M.L, Piris, M.A., Mason, D.Y., Marafioti, T. Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma. Haematologica. 2007 Aug; 92(8):1059-66.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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