Cdk7 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Cdk7 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Cdk7 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 7(CDK7) detection. Tested with WB in Human. Background: Cyclin-dependent kinase 7, also known as cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. The gene was assigned to human chromosome 5q13.2. Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition. |
| Immunogen | Immunogen: E Coli-derived human Cdk7 recombinant protein (Position: D31-F346). Human Cdk7 shares 94.9% and 96.1% amino acid (aa) sequence identity with mouse and rat Cdk7, respectively. Ig Type: Rabbit IgG |
| Other Names | [Cyclin-dependent kinase 7; 39 kDa protein kinase; CAK; CAK1; Cdk activating kinase; CDK-activating kinase 1; CDK-activating kinase; cdk7; CDK7_HUMAN; CDKN7; Cell division protein kinase 7; Cyclin dependent kinase 7; cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); Cyclin-dependent kinase 7; HCAK; Homolog of Xenopus MO15 Cdk activating kinase; Kinase subunit of CAK; MO15; MO15, Xenopus, homolog of; P39 Mo15; p39MO15; Serine threonine kinase Stk1; Serine/threonine protein kinase 1; Serine/threonine protein kinase MO15; STK1; TFIIH basal transcription factor complex kinase subunit; cyclin-dependent kinase 7], [CDK7; CDK7; CAK; CAK1; HCAK; MO15; STK1; CDKN7; p39MO15; CAK; CAK1; CDKN7; MO15; STK1; p39 Mo15] |
| Gene, Accession # | [CDK7], Gene ID: 1022, NCBI: NP_001790.1, UniProt: P50613 |
| Catalog # | MBS178225 |
| Price | $280 |
| Order / More Info | Cdk7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chen, J., Larochelle, S., Li, X., Suter, B. Xpd/Ercc2 regulates CAK activity and mitotic progression. Nature 424: 228-232, 2003. 2. Larochelle, S., Merrick, K. A., Terret, M.-E., Wohlbold, L., Barboza, N. M., Zhang, C., Shokat, K. M., Jallepalli, P. V., Fisher, R. P. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Molec. Cell 25: 839-850, 2007. 3. Levedakou, E. N., He, M., Baptist, E. W., Craven, R. J., Cance, W. G., Welcsh, P. L., Simmons, A., Naylor, S. L., Leach, R. L., Lewis, T. B., Bowcock, A., Liu, E. T. Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern. Oncogene 9: 1977-1988, 1994. 4. Shiekhattar, R., Mermelstein, F., Fisher, R. P., Drapkin, R., Dynlacht, B., Wessling, H. C., Morgan, D. O., Reinberg. Cdk-activating kinase complex is a component of human transcription factor TFIIH. Nature 374: 283-287, 1995. |
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