FAK Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAK
Clone[3D8-H11-E12]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.1 mL
Concentration1.89mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionEntrez Summary: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
ImmunogenImmunogen: Purified recombinant human FAK protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of FAK and does not cross-react with related proteins. Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily. Cotains 1 FERM domain. Contains 1 protein kinase domain.
Other Names[FADK 1; FADK; FAK 1; FAK 1; FAK related non kinase polypeptide; FAK1; FAK1_HUMAN; Focal adhesion kinase 1; Focal adhesion kinase 1; Focal adhesion Kinase; Focal adhesion kinase isoform FAK Del33; Focal adhesion kinase related nonkinase; FRNK; p125FAK; pp125FAK; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; Protein tyrosine kinase 2; Protein Tyrosine Kinase Cytoplasmic; Protein Tyrosine Kinase Cytoplasmic; Protein-tyrosine kinase 2; PTK 2; PTK 2; PTK2; PTK2 protein tyrosine kinase 2; PTK2 protein tyrosine kinase 2], [ptk2; FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK.]
Gene, Accession #[FAK], Gene ID: 5747, NCBI: NP_001186578.1, UniProt: Q05397
Catalog #MBS475430
Price$335
Order / More InfoFAK Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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