TLR9, Mouse Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TLR9, Mouse |
| Clone | 5G5 |
| Host Species | Mouse |
| Reactive Species | reactivity: mouse. cross reactivity: dog, human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), Immunoassay (IA), P, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody 5G5 reacts with the Toll-like receptor 9 (TLR9, CD289). TLRs are highly conserved throughout evolution and have been implicated in the innate defence to many pathogens. In Drosophila, toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. In mammals, TLRs identified as type I transmembrane signalling receptors with pattern recognition capabilities, have been implicated in the innate host defence to pathogens. As investigated so far all functional characterized TLR signal via the TLR/IL-1 receptor (IL-1R) pathway where recruitment of MyD88 seems to be essential. In contrast to cell-wall components, bacterial DNA is probably invisible for |
| Immunogen | n/a |
| Other Names | [TLR9; Toll-like receptor 9; toll-like receptor 9; toll-like receptor 9; CD_antigen: CD289], [TLR9; TLR9; CD289; UNQ5798/PRO19605] |
| Gene, Accession # | [TLR9], Gene ID: 54106, NCBI: AAZ95520.1 |
| Catalog # | MBS584246 |
| Price | $520 |
| Order / More Info | TLR9, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Ahmad-Nejad, P et al; Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur J Immunol 2002, 32: 1958 2. Rutz, M et al; Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. Eur J Immunol 2004, 34: 2541 3. Burgener, I et al; Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol 2008, 124; 184 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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