MADD Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMADD
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunoblot
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DescriptionSpecificity: Anti-MADD (CT) [Rabbit antibody to peptide corresponding to aa 1570-1588 of human MADD. Recognizes human and mouse MADD.]. This antibody recognizes human and mouse MADD (200-220 kD). MAP kinase-activating death domain protein (MADD) was initially identified as the type 1 tumor necrosis factor receptor (TNFR1). Overexpression of MADD activates MAP kinases ERK and JNK and induces the phosphorylation of cytosolic phospholipase A2. MADD shares 98% homology with DENN (differentially expressed in neoplasic vs. normal cells) which was recently identified as a substrate for c-jun N-terminal kinase 3 (JNK3). MADD has greather than 94% homology with a GDO/GTP exchange protein , Rab3-GEP, and it is 87% homologous with KIAA0358, a brain pr
ImmunogenAntigen: Peptide corresponding to aa 1570-1588 of human MADD. This peptide sequence is identical to that of DENN and differs by one amino acid with rat GDP/GTP exchange protein RAB3-GEP.
Other Names[MADD (CT); MADD], [MADD; DENN; DENN; IG20; RAB3GEP; FLJ35600; FLJ36300; KIAA0358]
Gene, Accession #Gene ID: 8567, NCBI: NP_001129416.1, UniProt: Q7KYV8
Catalog #MBS194115
Price$415
Order / More InfoMADD Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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