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Antigenic Specificity | CDK12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of CDK12 protein. CDK12 (Cyclin Dependent Kinase 12) is a Protein Coding gene. Among its related pathways are DNA Damage and Formation of HIV elongation complex in the absence of HIV Tat. Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates Ser-5 in CTD repeats that are already phosphorylated at Ser-7, but can also phosphorylate Ser-2. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MA |
Immunogen | Immunogen: Synthesized peptide derived from part region of human CDK12 protein at amino acid sequence of 50-130 |
Other Names | [Rabbit CDK12; Cyclin-dependent kinase 12; Cdc2-related kinase, arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12] |
Gene, Accession # | [CDK12], Gene ID: 51755, NCBI: NP_057591.2, UniProt: Q9NYV4 |
Catalog # | MBS9708668 |
Price | $130, $220, $325 |
Order / More Info | CDK12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |