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Antigenic Specificity | HDAC2 (Center), 410-439 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: chicken, mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HDAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the Central region of human HDAC2. This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. |
Immunogen | n/a |
Other Names | [Histone deacetylase 2; HD2; HDAC2] |
Gene, Accession # | [HDAC2], Gene ID: 3066, NCBI: NP_001518.3, UniProt: Q92769 |
Catalog # | MBS9205858 |
Price | $165, $370 |
Order / More Info | HDAC2 (Center), 410-439 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ishikawa, F., et al. Oncogene 29(6):909-919(2010) Bush, E.W., et al. Circ. Res. 106(2):272-284(2010) Krishnan, M., et al. Oncogene 29(2):305-312(2010) Lehmann, A., et al. BMC Cancer 9, 395 (2009) Hassig, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 95(7):3519-3524(1998) |