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Antigenic Specificity | ZYX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 0.5mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin (ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. |
Immunogen | Immunogen: Fusion protein of human ZYX |
Other Names | [ESP 2; ESP2; HED 2; HED2; ZYX; ZYX protein; Zyxin 2; Zyxin2] |
Gene, Accession # | [ZYX], Gene ID: 7791, NCBI: NP_001010972.1, UniProt: Q15942 |
Catalog # | MBS2562302 |
Price | $110, $150, $225 |
Order / More Info | ZYX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |