Caspase-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.2 mg/ml
ApplicationsWestern Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
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DescriptionBackground: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 (ICE, interleukin-1beta-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1beta and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis.
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 132 of human caspase-1
Other Names[CASP1; IL1BCE; P45; Interleukin-1 beta convertase; IL-1BC; IL1BC; p45; IL1B-convertase; CASP-1; ICE], [CASP1; CASP1; ICE; P45; IL1BC; IL1BC; IL1BCE; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme]
Gene, Accession #Gene ID: 834, NCBI: NP_150636
Catalog #MBS840546
Price$150, $360
Order / More InfoCaspase-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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