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Antigenic Specificity | Caspase-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.2 mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 (ICE, interleukin-1beta-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1beta and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 132 of human caspase-1 |
Other Names | [CASP1; IL1BCE; P45; Interleukin-1 beta convertase; IL-1BC; IL1BC; p45; IL1B-convertase; CASP-1; ICE], [CASP1; CASP1; ICE; P45; IL1BC; IL1BC; IL1BCE; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme] |
Gene, Accession # | Gene ID: 834, NCBI: NP_150636 |
Catalog # | MBS840546 |
Price | $150, $360 |
Order / More Info | Caspase-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |