RAD51 (Prognostic and Response to Chemotherapy Marker) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-RAD51 (Prognostic and Response to Chemotherapy Marker) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | RAD51 (Prognostic and Response to Chemotherapy Marker) |
| Clone | [RAD51/2701] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistology (Formalin-Fixed) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RAD51 is one of the key factors of DNA repair by homologous recombination and has been shown to have anti-apoptotic activity in tumor cells. RAD51 protein interacts with a variety of tumor suppressor proteins including p53, BRCA1 and BRCA2. Elevated expression of RAD51 enhances radio-resistance of human tumor cells. Overexpression of RAD51 protein in tumor cells renders them resistant against cytotoxic drugs like Cisplatin. RAD51 interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of RAD51. High-level expression of RAD51 has been observed in a variety of human malignancie |
| Immunogen | Immunogen: Recombinant fragment of human RAD51 protein (around aa 1-134) (exact sequence is proprietary) Positive Control: HeLa or MCF-7 Cells. Colon or Breast Carcinoma |
| Other Names | [RCA1/BRCA2 containing complex, subunit 5; BRCC5; DNA repair protein RAD51; FANCR; HsT16930; MRMV2; RAD51; RAD51 recombinase; RAD51A; RECA; RecA like protein; Recombination protein A] |
| Gene, Accession # | [RAD51], Gene ID: 5888, NCBI: NP_001157741.1, UniProt: Q06609 |
| Catalog # | MBS4380673 |
| Price | $190, $340, $340 |
| Order / More Info | RAD51 (Prognostic and Response to Chemotherapy Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Henning W, Stuerzbecher H-W (2003) Homologous recombination and cell cycle checkpoints: Rad51 in tumour progression and therapy resistance. Toxicology 193: 91-109 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies