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Antigenic Specificity | SCN5A (N-term), 42-70 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SCN5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human SCN5A. The protein encoded by this gene is an integral membraneprotein and tetrodotoxin-resistant voltage-gated sodium channelsubunit. This protein is found primarily in cardiac muscle and isresponsible for the initial upstroke of the action potential in anelectrocardiogram. Defects in this gene are a cause of long QTsyndrome type 3 (LQT3), an autosomal dominant cardiac disease.Alternative splicing results in several transcript variantsencoding different isoforms. |
Immunogen | n/a |
Other Names | [Sodium channel protein type 5 subunit alpha; HH1; Sodium channel protein cardiac muscle subunit alpha; Sodium channel protein type V subunit alpha; Voltage-gated sodium channel subunit alpha Nav15; SCN5A] |
Gene, Accession # | [SCN5A], Gene ID: 6331, NCBI: NP_000326.2, UniProt: Q14524 |
Catalog # | MBS9205102 |
Price | $165, $370 |
Order / More Info | SCN5A (N-term), 42-70 Antibody from MYBIOSOURCE INC. |
Product Specific References | Liu, M., et al. Circ. Res. 107(8):967-974(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) van Stuijvenberg, L., et al. DNA Cell Biol. 29(10):577-587(2010) House, C.D., et al. Cancer Res. 70(17):6957-6967(2010) Garcia-Castro, M., et al. Rev Esp Cardiol 63(7):856-859(2010) |