CD101 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD101
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.3mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total CD101 protein. Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4+ CD56+ leukemic tumor cells.
ImmunogenImmunogen: Synthetic peptide corresponding to internal residues of human CD101 Immunogen Type: Peptide
Other Names[V7; IGSF2; EWI-101]
Gene, Accession #[CD101], Gene ID: 9398, NCBI: NP_004249, UniProt: Q93033
Catalog #MBS9429579
Price$255
Order / More InfoCD101 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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