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Antigenic Specificity | CD101 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.3mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CD101 protein. Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4+ CD56+ leukemic tumor cells. |
Immunogen | Immunogen: Synthetic peptide corresponding to internal residues of human CD101 Immunogen Type: Peptide |
Other Names | [V7; IGSF2; EWI-101] |
Gene, Accession # | [CD101], Gene ID: 9398, NCBI: NP_004249, UniProt: Q93033 |
Catalog # | MBS9429579 |
Price | $255 |
Order / More Info | CD101 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |