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Antigenic Specificity | TBP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TBP protein. General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.Peterson M.G., Scien |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TBP. |
Other Names | [TATA binding factor; TATA sequence-binding protein; TATA-box binding protein; TATA-box factor; TFIID] |
Gene, Accession # | [TBP], Gene ID: 6908, NCBI: NP_001165556.1, UniProt: P20226 |
Catalog # | MBS9406272 |
Price | $200, $255 |
Order / More Info | TBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |