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Antigenic Specificity | Caspase 6 (Cleaved-Asp179) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Caspase 6 (Cleaved-Asp179) antibody detects endogenous levels of total Caspase 6 (Cleaved-Asp179). Description: Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated.Function: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.Subunit Structure: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit. Interacts with BIRC6/bruce.Post-translational Modifications: |
Immunogen | Immunogen: A synthesized peptide derived from human Caspase 6 (Cleaved-Asp179) Subcellular Location: Cytoplasm. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Dog Similarity: Pig (100%), Zebrafish (83%), Bovine (100%), Horse (100%), Dog (100%) |
Other Names | [Apoptotic protease Mch-2; Apoptotic protease MCH2; CASP-6; CASP6; CASP6_HUMAN; Caspase 6; Caspase 6 apoptosis related cysteine protease; Caspase 6, apoptosis related cysteine peptidase; Caspase-6 subunit p11; Mch2; OTTHUMP00000162742; OTTHUMP00000162743] |
Gene, Accession # | [CASP6], Gene ID: 839, NCBI: NP_001217.2, UniProt: P55212 |
Catalog # | MBS9601553 |
Price | $240, $280 |
Order / More Info | Caspase 6 (Cleaved-Asp179) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |