IRF2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IRF2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total IRF2 protein. Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.Itoh S., Nucleic Acids Res. 17:8372-8372(1989).Cha Y., J. Biol. Chem. 269:5279-5287(1994).Staal A., J. Cell. Physiol. 185:269-279(2000). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human IRF2. |
| Other Names | [IRF2; Interferon regulatory factor 2] |
| Gene, Accession # | [IRF2], Gene ID: 3660, NCBI: NP_002190.2, UniProt: P14316 |
| Catalog # | MBS9407914 |
| Price | $200, $255 |
| Order / More Info | IRF2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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