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Antigenic Specificity | Vitamin D3 Receptor (Ab-51) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Vitamin D3 Receptor protein. Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.Baker A.R., Proc. Natl. Acad. Sci. U.S.A. 85:3294-3298(1988).Goto H., Biochim. Biophys. Acta 1132:103-108(1992).Miyamoto K., Mol. Endocrinol. 11:1165-1179(1997). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized non-phosphopeptide derived from human Vitamin D3 Receptor around the phosphorylation site of serine 51 (R-R-S(p)-M-K). |
Other Names | [1,25-dihydroxyvitamin D3 receptor; NR1I1; vitamin D receptor; vitamin D3 receptor] |
Gene, Accession # | Gene ID: 7421, NCBI: NP_000367.1, UniProt: P11473 |
Catalog # | MBS9414617 |
Price | $200, $255 |
Order / More Info | Vitamin D3 Receptor (Ab-51) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |