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Antigenic Specificity | Rat ACE2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pathological role of ACE2 in the cardiovascular, renal and respiratory systems. ACE2 also has an important role in blood pressure control. This enzyme, an homolog of ACE, hydrolyzes angiotensin (Ang) I to produce Ang- (1-9), which is subsequently converted into Ang- (1-7) by a neutral endopeptidase and ACE. ACE2 releases Ang- (1-7) more efficiently than its catalysis of Ang- (1-9) by cleavage of Pro (7)-Phe (8) bound in Ang II. Thus, the major biologically active product of ACE2 is Ang- (1-7), which is considered to be a benef |
Immunogen | Immunogen: Recombinant Rat ACE2 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [ACE2; Angiotensin-converting enzyme 2; angiotensin-converting enzyme 2; angiotensin I converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH] |
Gene, Accession # | [ACE2 ], Gene ID: 59272 |
Catalog # | MBS2544701 |
Price | $215, $330, $500 |
Order / More Info | Rat ACE2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |