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Antigenic Specificity | Mbnl2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Mbnl2. It was validated on Western BlotTarget Description: Mbnl2 mediates pre-mRNA alternative splicing regulation. It acts either as activator or repressor of splicing on specific pre-mRNA targets. It inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. It antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. It seems to regulate expression and localization of ITGA3 by transporting it f |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of RAT Mbnl2 |
Other Names | [muscleblind-like protein 2; Muscleblind-like protein 2; muscleblind-like protein 2; muscleblind-like splicing regulator 2] |
Gene, Accession # | [MBNL2], Gene ID: 680445, NCBI: NP_001104534.1, UniProt: F2Z3T4 |
Catalog # | MBS3205564 |
Price | $335 |
Order / More Info | Mbnl2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |