Presenilin 1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Presenilin 1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | bovine, cat, human, monkey, porcine |
| Isotype | n/a |
| Format | biotin conjugate |
| Size | 0.1 mg |
| Concentration | 1.00-1.25 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), IMM, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | BIOTIN-Conjugated Presenilin 1 (Alzheimer disease 3) Antibody N-epitope. Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1-50 on Presenilin 1 (Alzheimer disease 3) protein. Expression: Expressed in a wide range of tissues including various regions of the brain, liver, spleen and lymph nodes. |
| Other Names | [AD3; FAD; Homo Sapiens Clone CC44 Senilin 1; Presenilin-1 CTF12; Protein S182; PS 1; PSEN1; S182], [PSEN1; PSEN1; AD3; FAD; PS1; PS-1; S182; AD3; PS1; PSNL1; PS-1; PS1-CTF12] |
| Gene, Accession # | Gene ID: 5663, NCBI: EAW81096.1, UniProt: P49768 |
| Catalog # | MBS544426 |
| Price | $495 |
| Order / More Info | Presenilin 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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