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Antigenic Specificity | LRP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.5 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total LRP1 protein. The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human low density lipoprotein receptor-related protein 1 |
Other Names | [APR; LRP; A2MR; CD91; APOER; TGFBR5; IGFBP3R] |
Gene, Accession # | [LRP1], Gene ID: 4035, NCBI: NP_002323.2, UniProt: Q07954 |
Catalog # | MBS9413973 |
Price | $255 |
Order / More Info | LRP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |