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Antigenic Specificity | SNX3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Also can bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2). Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo-selective subcomplex (CSC/VPS). May in part act as component of the SNX3-retromer complex which mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway (PubMed:21725319, PubMed:24344282). Promotes stability and cell surface expression of epithelial |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-162 of human SNX3 (NP 003786.1). |
Other Names | [SDP3; Grd19; MCOPS8] |
Gene, Accession # | [SNX3], Gene ID: 8724, NCBI: NP_003786.1, UniProt: O60493 |
Catalog # | MBS8546862 |
Price | $280 |
Order / More Info | SNX3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |