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Antigenic Specificity | CD3e (T-Cell Marker) |
Clone | [UCHT1] |
Host Species | Mouse |
Reactive Species | human, chimpanzee |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the -chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T ce |
Immunogen | Immunogen: Human infant thymocytes and peripheral blood lymphocytes from a Sezary Syndrome donor Cellular Localization: Cell Surface and Cytoplasmic |
Other Names | [CD3 epsilon; CD3 TCR complex; T cell antigen receptor complex epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE; TiT3 complex] |
Gene, Accession # | [CD3e], Gene ID: 916, NCBI: NP_000724.1, UniProt: P07766 |
Catalog # | MBS4380307 |
Price | $190, $340, $340 |
Order / More Info | CD3e (T-Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Mason DY et. al. Journal of Clinical Pathology, 1989, 42(11):1194-200. Beverley PC, Callard RE. Eur J Immunol. 1981; 11(4):329-334. |