Phospho-MAP4K4 (S801) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MAP4K4 (S801)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.34
ApplicationsDot Blot (DB), ELISA (EIA)
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DescriptionThis MAP4K4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S801 of human MAP4K4. M4K4, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta
Immunogenn/a
Other Names[Mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; Nck-interacting kinase; MAP4K4; HGK; KIAA0687; NIK]
Gene, Accession #[MAP4K4], Gene ID: 9448, NCBI: NP_001229488.1, UniProt: O95819
Catalog #MBS9201825
Price$150, $340
Order / More InfoPhospho-MAP4K4 (S801) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWright, J.H., et al., Mol. Cell. Biol. 23(6):2068-2082 (2003). Yao, Z., et al., J. Biol. Chem. 274(4):2118-2125 (1999). Ishikawa, K., et al., DNA Res. 5(3):169-176 (1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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