Caspase-3 (Pro and Active) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Caspase-3 (Pro and Active) |
| Clone | [ABM1C12] |
| Host Species | Mouse |
| Reactive Species | human (predicted reactivity: mouse, rat |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western blot analysis: 2-4 ug/ml. Immunohistochemical analysis: 5-10 Ug/ml. FACS analysis: 0.5-1 ug/10^6 cells |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Caspases are a member of the cysteine-aspartic acid protease family. Caspase-3 (31 kDa) is an executionary caspase which directly cleaves and activates poly(ADP-ribose) polymerase (PARP), sterol regulatory element binding proteins (SREBPs) or it can also interact with other caspases like caspase-6, -7 and -9. Increased levels of caspase-3 are involved in Huntington Disease-associated cell death. Caspase-3 is the principal caspase in mediating the cleavage of amyloid-beta 4A precursor protein (APP), which is related with neuronal death in Alzheimer's disease. Like other caspases, caspase-3 is also synthesized as a zymogen procaspase which is activated by specific proteolytic cleavage. High levels of caspase-3 are observed in lung, spleen, he |
| Immunogen | Immunogen: Full length recombinant Caspase-3 protein was used as the immunogen for this antibody |
| Other Names | [Casp3,Cpp32], [Casp3; Casp3; CC3; AC-3; Lice; Yama; mldy; CPP32; SCA-1; CASP-3; CPP-32; Apopain; Caspase-3; A830040C14Rik; Cpp32; CASP-3; CPP-32; SCA-1] |
| Gene, Accession # | Gene ID: 12367, NCBI: NP_001271338.1, UniProt: P70677 |
| Catalog # | MBS668032 |
| Price | $290 |
| Order / More Info | Caspase-3 (Pro and Active) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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