PCSK9 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PCSK9 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC)-Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Polyclonal Antibody to detect PCSK9 in human samples. Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9), is an enzyme which in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3). |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal (671-687aa AVTAVAICCRSRHLAQA) of human PCSK9. Positive Control: Western blot: A549, HeLa, U87, PANC Cell Lysate. IHC-P: Human Intestinal Cancer Tissue. |
| Other Names | [PCSK9; FH3; HCHOLA3; LDLCQ1; NARC1; PC9; FH3; NARC-1; HCHOLA3; PC9; Proprotein convertase 9; Subtilisin/kexin-like protease PC9; Hypercholesterolemia; autosomal dominant 3; Neural apoptosis-regulated convertase 1;], [PCSK9; PCSK9; FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3; NARC1; NARC-1; PC9] |
| Gene, Accession # | [PCSK9], Gene ID: 255738, NCBI: NP_777596.2, UniProt: Q8NBP7 |
| Catalog # | MBS840800 |
| Price | $375 |
| Order / More Info | PCSK9 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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