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Antigenic Specificity | CASP3 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, goat, guinea pig, horse, human, mouse, porcine, rabbit, rat, sheep |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against CASP3. It was validated on Western BlotTarget Description: CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzhe |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CASP3 |
Other Names | [caspase-3 isoform a preproprotein; Caspase-3; caspase-3; caspase 3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1] |
Gene, Accession # | [CASP3], Gene ID: 836, NCBI: NP_116786, UniProt: P42574 |
Catalog # | MBS3214143 |
Price | $335 |
Order / More Info | CASP3 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |