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Antigenic Specificity | CXCR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. |
Immunogen | Immunogen: Recombinant human C-X-C chemokine receptor type 4 protrin Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6279 / sc-6191 / sc-6190 / sc-9046 |
Other Names | [C-X-C chemokine receptor type 4; CXC-R4; FB22; Leukocyte-derived seven transmembrane domain receptor; CXCR4], [CXCR4; CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; D2S201E; CXC-R4; CXCR-4; LESTR; LAP-3; LPS-associated protein 3; SDF-1 receptor] |
Gene, Accession # | [CXCR4], Gene ID: 7852, NCBI: NP_001008540.1, UniProt: P61073 |
Catalog # | MBS1492652 |
Price | $160, $235 |
Order / More Info | CXCR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |