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Antigenic Specificity | PMAIP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
Immunogen | Immunogen: Recombinant human Phorbol-12-myristate-13-acetate-induced protein 1 protein |
Other Names | [Phorbol-12-myristate-13-acetate-induced protein; 1PMA-induced protein 1; Immediate-early-response protein APR; Protein Noxa; PMAIP1; NOXA] |
Gene, Accession # | [PMAIP1], Gene ID: 5366, NCBI: NP_066950.1, UniProt: Q13794 |
Catalog # | MBS7044800 |
Price | $160, $235 |
Order / More Info | PMAIP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |