Edit |   |
---|---|
Antigenic Specificity | CaV1.3 |
Clone | [S38-8] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | PerCP conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~250kDa. No cross-reactivity against Cav1.2 Scientific Background: Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical |
Immunogen | n/a |
Other Names | [alpha-1 polypeptide; CAC1D_HUMAN; CACH3; CACN4; CACNA 1D; Cacna1d; CACNL1A2; Calcium channel; Calcium channel L type alpha 1 polypeptide isoform 2; Calcium channel neuroendocrine/brain type alpha 1 subunit; Calcium channel voltage dependent L type alpha 1], [Cacna1d; Cacna1d; Cach3; Cacn4; Cacnl1a2; Cchl1a2; RBD] |
Gene, Accession # | Gene ID: 29716, NCBI: NP_058994.1, UniProt: P27732 |
Catalog # | MBS800005 |
Price | $435 |
Order / More Info | CaV1.3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.:Sunderland, MA USA. 2. www.iochannels.org 3. Zhang Z., et al. (2005) Circulation 112: 1936-1944. 4. Johnson S.L. and Marcotti W. (2008) The Journal of Physiology. 586: 1029-1042. |