SHOC2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SHOC2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SHOC2 Antibody: SHOC2 protein participates in protein binding / transferase activity in the fibroblast growth factor receptor signaling pathway and Ras protein signal transduction. It is a widely expressed protein composed almost entirely of leucine-rich repeats (LRR), with a lysine-rich sequence at the amino terminus and cytoplasmically localized. SHOC2 acts as a positive modulator of the RAS-MAPK signaling cascade, which is elicited by EGL-15 and LET-23 and mediated by LET-60. SHOC2 together with protein phosphatase 1c (PP1c) forms a highly specific M-Ras effector complex and is essential for activation of the MAPK pathway by growth factors. Furthermore, in tumor cells with Ras gene mutations, inhibition of SHOC2 expression inhibits MAPK, |
| Immunogen | Immunogen: SHOC2 antibody was raised against a 21 amino acid synthetic peptide near the amino terminus of human SHOC2. Buffer: SHOC2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [SHOC2; SOC2; SUR8; SIAA0862; KIAA0862; Leucine-rich repeat protein SHOC-2; Protein soc-2 homolog; soc-2 suppressor of clear homolog (C. elegans)], [SHOC2; SHOC2; SOC2; SUR8; SIAA0862; KIAA0862] |
| Gene, Accession # | [SHOC2], Gene ID: 8036, NCBI: NP_031399, UniProt: Q9UQ13 |
| Catalog # | MBS150121 |
| Price | $375 |
| Order / More Info | SHOC2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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