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Antigenic Specificity | APEX2 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APEX nuclease (apurinic/apyrimidinic endonuclease) 2Target Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision r |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human APEX2 |
Other Names | [DNA-(apurinic or apyrimidinic site) lyase 2 isoform 1; DNA-(apurinic or apyrimidinic site) lyase 2; DNA-(apurinic or apyrimidinic site) lyase 2; apurinic/apyrimidinic endodeoxyribonuclease 2; AP endonuclease XTH2; APEX nuclease 2; APEX nuclease-like 2; Apurinic-apyrimidinic endonuclease 2; AP endonuclease 2] |
Gene, Accession # | [APEX2], Gene ID: 27301, NCBI: NP_055296, UniProt: Q9UBZ4 |
Catalog # | MBS3216690 |
Price | $335 |
Order / More Info | APEX2 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |