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Antigenic Specificity | Mouse BAD (Center S112/S111/Y113) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse; predicted reactivity: rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This mouse BAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of mouse BAD. Description: BAD promotes cell death. It successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. Background: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity |
Immunogen | n/a |
Other Names | [Bcl2-associated agonist of cell death; BAD; Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; Bad; Bbc6] |
Gene, Accession # | [Bad], Gene ID: 12015, NCBI: NP_031548.1, UniProt: Q61337 |
Catalog # | MBS9217100 |
Price | $165, $370 |
Order / More Info | Mouse BAD (Center S112/S111/Y113) Antibody from MYBIOSOURCE INC. |
Product Specific References | Santidrian, A.F., et al. Blood 116 (16):3023-3032 (2010). Frenzel, A., et al. Blood 115 (5):995-1005 (2010). Quoyer, J., et al. J. Biol. Chem. 285 (3):1989-2002 (2010). Polzien, L., et al. J. Biol. Chem. 284 (41):28004-28020 (2009). Wu, X., et al. Diabetologia 52 (10):2130-2141 (2009). |