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Antigenic Specificity | AKT1 |
Clone | [960CT4.5.1] |
Host Species | Mouse |
Reactive Species | human (predicted reactivity: bovine, mouse, rat) |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This AKT1 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 430-460 region of human AKT1. AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell su |
Immunogen | n/a |
Other Names | [RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT1; PKB; RAC] |
Gene, Accession # | [AKT1], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749 |
Catalog # | MBS9200557 |
Price | $370 |
Order / More Info | AKT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Jones P.F., et al. Proc. Natl. Acad. Sci. U.S.A. 88:4171-4175(1991). Matsubara A., et al. Diabetologia 44:910-913(2001). Ota T., et al. Nat. Genet. 36:40-45(2004). Goshima N., et al. Nat. Methods 5:1011-1017(2008). Coffer P.J., et al. Eur. J. Biochem. 201:475-481(1991). |