Hsp70 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHsp70
Clonepolyclonal
Host SpeciesChicken
Reactive Specieshuman, rat, mouse
Isotypen/a
FormatPerCP conjugate
Size0.1 mg
Concentration1mg/mL
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionBackground Info: Hsp70 Scientific Background: Hsp70 genes encode abundant heat-inducible 70-kDa hsps (hsp70s). In most eukaryotes hsp70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 5O% identity (1). The N-terminal two thirds of hsp70s are more conserved than the C-terminal third. Hsp70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (2). When hsc70 (constitutively expressed) present in mammalian cells was truncated, A
Immunogenn/a
Other Names[Hsp70 1; Hsp70 2; Hsp70.1; Hsp72; HSPA1; HSPA1A; HSPA1B], [HSPA1A; HSPA1A; HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HEL-S-103; HSPA1; HSX70HSPA1B; HSP70-1/HSP70-2; HSP70.1/HSP70.2]
Gene, Accession #Gene ID: 3303, NCBI: NP_005336.3, UniProt: P08107
Catalog #MBS804988
Price$435
Order / More InfoHsp70 Antibody from MYBIOSOURCE INC.
Product Specific References1. Balashova N. et al. (2005) J Biol Chem 280:2186-96. 2. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993) J. Mol. Evol.38 (1): 1-17. 2. Rothman J. (1989) Cell 59: 591 -601. 3. DeLuca-Flaherty et al. (1990) Cell 62: 875-887. 4. Bork P., Sander C. & Valencia A. (1992) Proc. Nut1 Acad. Sci. USA 89: 7290-7294. 5. Fink A.L. (1999) Physiol. Rev. 79: 425-449.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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