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Antigenic Specificity | Synaptotagmin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified Synaptotagmin Antibody to detect Synaptotagmin which binds calcium in a complex with negatively charged phospholipids. Background: The synaptotagmins are integral membrane proteins of synaptic vesicles thomught to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first C2 domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 298 of rat Synaptotagmin. Positive Control: Rat kidney tissue lysate |
Other Names | [Synaptotagmin-1; Synaptotagmin I; SytI; p65; Syt1], [Syt1; Syt1; P65; SytI] |
Gene, Accession # | Gene ID: 25716, NCBI: NP_001028852.2, UniProt: P21707 |
Catalog # | MBS840283 |
Price | $150, $305 |
Order / More Info | Synaptotagmin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |