Edit |   |
---|---|
Antigenic Specificity | GFRA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total GFRA1 protein. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Synthetic peptide corresponding to a region derived from 370-384 amino acids of Human GDNF family receptor alpha 1 |
Other Names | [GDNF family receptor alpha 1, GDNFR, RET1L, RETL1, TRNR1, GDNFRA, GFR-ALPHA-1] |
Gene, Accession # | [GFRA1], Gene ID: 2674, NCBI: NP_005255 |
Catalog # | MBS9405499 |
Price | $200, $255 |
Order / More Info | GFRA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |